condition Nephrology

Overview

Nephrology is the branch of medicine that studies and treats kidney diseases. At least 1 in every 75 adults in the United States has chronic kidney disease (CKD). Diabetes, high blood pressure, obesity, and other factors can damage the kidneys over time. Once damaged, the kidneys are not able to remove waste, balance minerals, or help maintain blood pressure. Symptoms can be hard to notice at first. They can include foamy urine, itchy skin, nausea, and needing to urinate more or less often than usual. If the damage continues, the kidneys may no longer be able to work at all. Dialysis is needed to remove waste and extra water from the body when the kidneys no longer work. Many different medications may be needed to balance minerals and help make red blood cells.

Drug Therapies

  • Calcitriol

    calcitriol

    Calcitriol is a synthetic vitamin D analog that helps regulate the absorption of calcium from the gastrointestinal tract and its use in the body.
    Manufacturer:
    Misc
    Route of Administration: 
    Oral
    Site of Care:
    Outpatient
    Website: 
      Enrollment Forms:
      Synergen Prescription Form

      Approved Indication:

      • managing secondary hyperparathyroidism and resultant metabolic bone disease in patients with moderate to severe chronic renal failure (Ccr 15-55 mL/min)
      • managing hypocalcemia and the resultant metabolic bone disease in patients undergoing chronic renal dialysis
      • managing hypocalcemia and its clinical manifestations in patients with postsurgical hypoparathyroidism, idiopathic hypoparathyroidism, and pseudohypoparathyroidism

      Conditions:

      • Hypocalcemia
      • Secondary Hyperparathyroidism

        Therapeutic Area:

        • Oncology
        less details
      • Cinacalcet

        cinacalcet

        Cinacalcet is a calcium-sensing receptor agonist that lowers circulating parathyroid hormone and serum calcium levels to help prevent progressive bone disease.
        Manufacturer:
        Misc
        Route of Administration: 
        Oral
        Site of Care:
        Outpatient
        Website: 
          Enrollment Forms:
          Synergen Prescription Form

          Approved Indication:

          • secondary hyperparathyroidism in adult patients with chronic kidney disease on dialysis
          • hypercalcemia in adult patients with parathyroid carcinoma
          • hypercalcemia in adult patients with primary hyperparathyroidism for whom parathyroidectomy would be indicated on the basis of serum calcium levels but who are unable to undergo parathyroidectomy

          Conditions:

          • Hypercalcemia
          • Secondary Hyperparathyroidism

            Therapeutic Area:

            • Oncology
            less details
          • Epogen

            Epogen (epoetin alfa)

            Epogen (epoetin alfa) is a synthetic protein that promotes the production of new red blood cells in patients with certain types of anemia.
            Manufacturer:
            Amgen
            Route of Administration: 
            Subcutaneous, Intravenous
            Site of Care:
            Outpatient
            Website: 
            • https://www.epogen.com
            phone: 
            866-264-2778
            Enrollment Forms:
            Synergen Prescription Form

            Approved Indication:

            • treatment of anemia due to chronci kidney disease in patients on dialysis and not on dialysis
            • treatment of anemia due to zidovudine in patients with HIV infection
            • treatment of anemia due to the effects of concomitant myelosuppressive chemotherapy (upon initiation, a minimum of two additional months of planned chemotherapy required)
            • reducing allogenic red blood cell transfusions in patients undergoing elective, noncardiac, nonvascular surgery

            Conditions:

            • Anemia

              Therapeutic Area:

              • Nephrology
              • Oncology
              less details
            • Feraheme

              Feraheme (ferumoxytol)

              Feraheme (ferumoxytol) is an iron oxide infusion used to treat anemia by supporting the formation of hemoglobin.
              Manufacturer:
              Amag Pharmaceuticals
              Route of Administration: 
              Intravenous
              Site of Care:
              Outpatient
              Website: 
              • https://feraheme.com
              phone: 
              1-844-635-2624
              Enrollment Forms:
              Synergen Prescription Form
              Patient Support Form

              Approved Indication:

              treatment of iron deficiency anemia in adult patients with chronic kidney disease

              Conditions:

              • Anemia

                Therapeutic Area:

                • Nephrology
                less details
              • Fosrenol

                Fosrenol (lanthanum carbonate)

                Fosrenol (lanthanum carbonate) is a lanthanum salt that binds to phosphous in the GI tract to prevent its absorption and to lower its levels in the blood.
                Manufacturer:
                Misc.
                Route of Administration: 
                Oral
                Site of Care:
                Outpatient
                Website: 
                  Enrollment Forms:
                  Synergen Prescription Form

                  Conditions:

                  • Hyperphosphatemia
                  • Chronic Kidney Disease

                    Therapeutic Area:

                    • Endocrinology
                    • Nephrology
                    less details
                  • Injectafer

                    Injectafer (ferric carboxymaltose)

                    Injectafer (ferric carboxymaltose) is an iron infusion used to treat anemia by supporting the formation of hemoglobin.
                    Manufacturer:
                    Daiichi-Sankyo
                    Route of Administration: 
                    Intravenous
                    Site of Care:
                    Outpatient
                    Website: 
                    • https://injectafer.com
                    phone: 
                    866-4-DSI-NOW (1-866-437-4669)
                    Enrollment Forms:
                    Synergen Prescription Form
                    Patient Support Form

                    Approved Indication:

                    • treatment of iron deficiency anemia in adult and pediatric patients 1 year of age and older who have either intolerance or an unsatisfactory response to oral iron
                    • treatment of iron deficiency anemia in adult patients with non-dialysis dependent chronic kidney disease
                    • treatment of iron deficiency in adult patients with heart failure and New York Heart Association class II/III to improve exercise capacity

                    Conditions:

                    • Iron Deficiency Anemia

                      Therapeutic Area:

                      • Nephrology
                      less details
                    • PhosLo

                      PhosLo (calcium acetate)

                      PhosLo (calcium acetate) is a calcium salt given to decrease the absorption of phosphorus from the gastrointestinal tract in patients with chronic kidney disease and high serum phosphorus levels.
                      Manufacturer:
                      Misc
                      Route of Administration: 
                      Oral
                      Site of Care:
                      Outpatient
                      Website: 
                        Enrollment Forms:
                        Synergen Prescription Form

                        Approved Indication:

                        reduction of serum phosphorus in patients with end stage renal disease

                        Conditions:

                        • Hyperphosphatemia
                        • Chronic Kidney Disease

                          Therapeutic Area:

                          • Endocrinology
                          • Nephrology
                          less details
                        • Procrit

                          Procrit (epoetin alfa)

                          Procrit (epoetin alfa) is a synthetic protein that promotes the production of new red blood cells in patients with certain types of anemia.
                          Manufacturer:
                          Johnson & Johnson
                          Route of Administration: 
                          Subcutaneous, Intravenous
                          Site of Care:
                          Outpatient
                          Website: 
                          • https://www.procrit.com
                          Enrollment Forms:
                          Synergen Prescription Form

                          Approved Indication:

                          • treatment of anemia due to chronci kidney disease in patients on dialysis and not on dialysis
                          • treatment of anemia due to zidovudine in patients with HIV infection
                          • treatment of anemia due to the effects of concomitant myelosuppressive chemotherapy (upon initiation, a minimum of two additional months of planned chemotherapy required)
                          • reducing allogenic red blood cell transfusions in patients undergoing elective, noncardiac, nonvascular surgery

                          Conditions:

                          • Anemia

                            Therapeutic Area:

                            • Nephrology
                            • Oncology
                            less details
                          • Renvela

                            Renvela (sevelamer carbonate)

                            Renvela (sevelamer) is a non-metallic, non-calcium-based binding agent given to decrease the absorption of phosphorus from the gastrointestinal tract in patients with chronic kidney disease and high serum phosphorus levels.
                            Manufacturer:
                            Sanofi
                            Route of Administration: 
                            Oral
                            Site of Care:
                            Outpatient
                            Website: 
                            • https://www.renvela.com
                            Enrollment Forms:
                            Synergen Prescription Form

                            Approved Indication:

                            control of serum phosphorus in adults and children 6 years of age and older with chronic kidney disease on dialysis

                            Conditions:

                            • Hyperphosphatemia
                            • Chronic Kidney Disease

                              Therapeutic Area:

                              • Endocrinology
                              • Nephrology
                              less details
                            • Retacrit

                              Retacrit (epoetin alfa-epbx)

                              Retacrit (epoetin alfa-epbx) is a biosimilar to Epogen. Like Epogen, Retacrit is a synthetic protein that promotes the production of new red blood cells in patients with certain types of anemia.
                              Manufacturer:
                              Pfizer
                              Route of Administration: 
                              Subcutaneous, Intravenous
                              Site of Care:
                              Outpatient
                              Website: 
                              • https://retacrit.pfizerpro.com
                              phone: 
                              1-877-744-5675
                              Enrollment Forms:
                              Synergen Prescription Form
                              Patient Support Form

                              Approved Indication:

                              • treatment of anemia due to chronci kidney disease in patients on dialysis and not on dialysis
                              • treatment of anemia due to zidovudine in patients with HIV infection
                              • treatment of anemia due to the effects of concomitant myelosuppressive chemotherapy (upon initiation, a minimum of two additional months of planned chemotherapy required)
                              • reducing allogenic red blood cell transfusions in patients undergoing elective, noncardiac, nonvascular surgery

                              Conditions:

                              • Anemia

                                Therapeutic Area:

                                • Nephrology
                                • Oncology
                                less details
                              • Vafseo

                                Vafseo (vadadustat)

                                Vafseo (vadadustat) inhibits the enzyme hypoxia-inducible factor prolyl hydroxylase to increase levels of erythropoietin and promote the production of red blood cells in patients with anemia due to kidney failure.
                                Manufacturer:
                                Akebia Therapeutics
                                Route of Administration: 
                                Oral
                                Site of Care:
                                Outpatient
                                Website: 
                                • https://www.vafseo.com
                                phone: 
                                1-855-686-8601
                                Enrollment Forms:
                                Synergen Prescription Form
                                Patient Support Form

                                Approved Indication:

                                treatment of anemia due to chronic kidney disease in adults who have been receiving dialysis for at least three months

                                Conditions:

                                • Anemia
                                • Chronic Kidney Disease

                                  Therapeutic Area:

                                  • Nephrology
                                  less details
                                • Venofer

                                  Venofer (iron sucrose)

                                  Venofer (iron sucrose) is an iron infusion used to treat anemia by supporting the formation of hemoglobin.
                                  Manufacturer:
                                  American Regent
                                  Route of Administration: 
                                  Intravenous
                                  Site of Care:
                                  Outpatient
                                  Website: 
                                  • https://www.venofer.com
                                  phone: 
                                  877-448-4766
                                  Enrollment Forms:
                                  Synergen Prescription Form
                                  Patient Support Form

                                  Approved Indication:

                                  treatment of iron deficiency anemia in adult patients with chronic kidney disease

                                  Conditions:

                                  • Iron Deficiency Anemia

                                    Therapeutic Area:

                                    • Nephrology
                                    less details
                                  • Xphozah

                                    Xphozah (tenapanor)

                                    Xphozah (tenapanor) inhibits an exchange protein in the lining of the colon and small intestine, preventing absorption of sodium and phosphate from the GI tract. Xphozah does not directly bind phosphate but is used in addition to (and occasionally in place of) direct phosphate binders.
                                    Manufacturer:
                                    Ardelyx
                                    Route of Administration: 
                                    Oral
                                    Site of Care:
                                    Outpatient
                                    Website: 
                                    • https://xphozah-hcp.com/
                                    phone: 
                                    877-527-3927
                                    Enrollment Forms:
                                    Synergen Prescription Form
                                    Patient Support Form

                                    Approved Indication:

                                    reduce serum phosphorus in adults with chronic kidney disease (CKD) on dialysis as add-on therapy in patients who have an inadequate response to phosphate binders or who are intolerant of any dose of phosphate binder therapy

                                    Conditions:

                                    • Chronic Kidney Disease

                                      Therapeutic Area:

                                      • Nephrology
                                      less details

                                    Resources

                                    Understanding a diagnosis can feel overwhelming. These resources link to well-established organizations, for in-depth education, research, and support.

                                    American Kidney Fund
                                    Georgia Transplant Foundation
                                    National Kidney Foundation

                                    Stay Connected

                                    Get the latest news and updates

                                    Contact Us Now