condition Hepatitis B

Overview

Hepatitis B is an infection caused by the hepatitis B virus. The virus spreads through contact with infected blood or other body fluids – like during sex without a condom or by sharing things like razors. Pregnant women with hepatitis B (HBV) can pass the virus to their newborn during birth. After being exposed, many adults with strong immune systems can fight off the virus without treatment, but if a blood test shows HBV six months later, the infection is now chronic and needs to be treated. Babies who get infected are very likely – over 90% – to develop chronic HBV. If not treated, chronic HBV will continue to damage the liver and can lead to serious problems like cirrhosis, liver failure, or liver cancer. People may not notice symptoms of acute HBV, but these can include fever, muscle pains, nausea and vomiting, light-colored stool, and/or dark or “tea-colored” urine. Chronic HBV infection does not usually show symptoms, but yellow skin, stomach swelling, or other signs of liver failure should be reported to a doctor right away. Chronic hepatitis B cannot be cured, but it can be prevented or controlled. Three vaccines are available to prevent infection, and several medications can stop the hepatitis B virus from multiplying and continuing to harm the liver.

Drug Therapies

  • Entecavir

    entecavir

    Entecavir is an antiviral medication approved to treat chronic hepatitis B infections in patients with or without decompensated liver disease.
    Manufacturer:
    Misc
    Route of Administration: 
    Oral
    Site of Care:
    Outpatient
    Website: 
      Enrollment Forms:
      Synergen Prescription Form

      Approved Indication:

      treatment of chronic hepatitis B virus infection in adults and children at least 2 years of age with evidence of active viral replication and either evidence of persistent elevations in serum aminotransferases (ALT or AST) or histologically active disease

      Conditions:

      • Chronic Viral Hepatitis B

      Therapeutic Area:

      • Gastroenterology
      • Infectious Disease
      • Hepatology

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    • Tenofovir DF

      tenofovir disoproxil fumarate

      Tenofovir disoproxil fumarate is an antiviral medication approved to treat HIV and chronic hepatitis B infections in patients with or without decompensated liver disease.
      Manufacturer:
      Misc
      Route of Administration: 
      Oral
      Site of Care:
      Outpatient
      Website: 
        Enrollment Forms:
        Synergen Prescription Form

        Approved Indication:

        • in combination with other antiretroviral agents for the treatment of HIV-1 infection in adults and pediatric patients 2 years of age and older weighing at least 10 kg
        • treatment of chronic hepatitis B in adults and pediatric patients 2 years and older weighing at least 10 kg

        Conditions:

        • Chronic Viral Hepatitis B
        • HIV

        Therapeutic Area:

        • Gastroenterology
        • Infectious Disease
        • Hepatology

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      • Vemlidy

        Vemlidy (tenofovir alafenamide)

        Vemlidy (tenofovir alafenamide) is an antiviral medication approved to trea chronic hepatitis B infections in patients with preserved kidney and liver function.
        Manufacturer:
        Gilead
        Route of Administration: 
        Oral
        Site of Care:
        Outpatient
        Website: 
        • https://www.vemlidyhcp.com/
        phone: 
        1-855-769-7284
        Enrollment Forms:
        Synergen Prescription Form
        Patient Support Form

        Approved Indication:

        treatment of chronic hepatitis B virus infection in adults and pediatric patients 6 years of age and older and weighing at least 25 kg with compensated liver disease

        Conditions:

        • Chronic Viral Hepatitis B

        Therapeutic Area:

        • Gastroenterology
        • Hepatology
        • Infectious Disease

        less details

      Resources

      Understanding a diagnosis can feel overwhelming. These resources link to well-established organizations, for in-depth education, research, and support.

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